Peptide Database

Peptide NameL5A

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC85H144N36O20S4

DescriptionStandard

        RGGRACYCRRRFCVCVGR
    

Molecular Weight2118.54 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 5.46

Charge Density (pH 7.0) 0.3177

GRAVY Index-0.36

Hydrophobic Moment 0.39

Boman Index-0.46

Instability Index86.54

Aliphatic Index 37.78

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 949.65

LogP -11.64

H-bond Donors 42.0

H-bond Acceptors 30.0

Rotatable Bonds 69.0

Heavy Atoms 145.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359348 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyProtegrin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli ATCC 25922 or ML35p or BW 25113

Activity0.125-0.5 μM

MethodMIC

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