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MYP_130680
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Basic Information
AdDLP (A. dehalogenans defensin-like peptide; Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
51 amino acids
C226H371N69O74S6
Standard
Sequence
VNPSYRLDPESRPQCEAHCGQLGMRLGAIVIMGTATGCVCEPKEAATPESR
Physicochemical Analysis
5431.17 Da
5.64
-1.21
-1.54
-0.0236
-0.33
0.43
-0.04
30.19
65.10
0.0196
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2271.35
-27.73
81.0
80.0
174.0
375.0
7.0
53.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077610 VERIFIED: YES
Provenance & Taxonomy
Anaeromyxobacter dehalogenans [Bacterium]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibacterial Antifungal Antiparasitic Antimicrobial
PaperPubMed PMID: 19615342 PMID19615342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19615342/
RECORD: Rec_0086549 VERIFIED: YES
Provenance & Taxonomy
Anaeromyxobacter dehalogenans [Bacterium]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiparasitic
P. falciparum ookinetes. Structure is predicted as an helix-beta fold based on homolog modeling
PaperAdDLP, a bacterial defensin-like peptide, exhibits anti-Plasmodium activity.
RECORD: Rec_0104112 VERIFIED: YES
Provenance & Taxonomy
Anaeromyxobacter dehalogenans [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic Antiprotozoal
Plasmodium berghei
PMID19615342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19615342/
RECORD: Rec_0202777 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
AdDLP
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum
10 μM
Percent inhibition; Microscopy (Giemsa staining)
PMID19615342 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19615342/
RECORD: Rec_0247229 VERIFIED: YES
Provenance & Taxonomy
Anaeromyxobacter dehalogenans [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID19463738 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463738/
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