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MYP_130610
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Basic Information
Beta-neoendorphin
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
9 amino acids
C54H77N13O12
Standard
Sequence
YGGFLRKYP
Physicochemical Analysis
1100.27 Da
9.70
1.76
1.55
0.1952
-0.76
0.46
-0.02
48.28
43.33
0.3333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
415.71
-1.38
15.0
14.0
32.0
79.0
4.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036444 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Beta-neoendorphin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Beta-neoendorphin (Rattus norvegicus): PMID 3858883 PMID3858883 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3858883/
RECORD: Rec_0064987 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]
Opioid
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0075225 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Enkephalin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperMinamino N., Kangawa K., Chino N., Sakapibara S., Matsuo H.. Beta-neo-endorphin, a new hypothalamic "big" Leu-enkephalin of porcine origin: its purification and the complete amino acid sequence. Biochem. Biophys. Res. Commun., 99, 864-870, 1981.
RECORD: Rec_0083075 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Opioid
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0087523 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Opioid
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
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