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MYP_130592
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Basic Information
Exendin 3
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Regulatory peptide ▸ Biological modulation
Standard
39 amino acids
C184H281N49O62S
Standard
Sequence
HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS
Physicochemical Analysis
4203.56 Da
4.64
-3.14
-3.41
-0.0805
-0.70
0.71
-0.01
68.67
52.56
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1764.19
-21.03
59.0
61.0
134.0
296.0
9.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112636 VERIFIED: YES
Provenance & Taxonomy
Heloderma horridum [Animal]
Exendin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Radiolabelling of exendin 3 at position 1 (histidine)
Bio-Activity Profile
GLP-1 agonist
Scintigraphy
NEDH Rats (rat tumour model), in vivo; 6480 s
PMID11976797 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976797/
RECORD: Rec_0117647 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0128545 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0230500 VERIFIED: YES
Provenance & Taxonomy
Heloderma horridum horridum [Animal]
Exendin
8552
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Cardiovascular Receptor modulation
Experimental: 13±3.2 minutes; /780 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Exendin-3 (Heloderma horridum horridum): PMID 11976797 PMID11976797 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976797/
RECORD: Rec_0259121 VERIFIED: NO
Provenance & Taxonomy
Gila monster [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone