Peptide Database

Peptide NameApidaecins type 22 [Cleaved into: Apidaecin-1B (Apidaecin IB); Apidaecin-1A (Apidaecin IA)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC735H1160N234O202S

DescriptionStandard

        MKNFALAILVVTFVVAVFGNTNLDPPTRPTRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRLRREAEPEAEPGNNRPVYIPQPRPPHPRI
    

Molecular Weight16538.59 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.89

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0409

GRAVY Index-1.20

Hydrophobic Moment 0.50

Boman Index-0.27

Instability Index69.59

Aliphatic Index 60.97

Aromaticity 0.0486

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6861.80

LogP -67.09

H-bond Donors 221.0

H-bond Acceptors 213.0

Rotatable Bonds 492.0

Heavy Atoms 1172.0

Ring Count 46.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232292 VERIFIED: YES

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyApidaecin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Non-hemolytic

TargetGram-negative bacteria