Peptide Database

Peptide NameIr-Def1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC176H271N59O45S6

DescriptionStandard

        SYNCPFQKHKCHRHCKSIGHIAGYCGGFRNRTCICV
    

Molecular Weight4125.79 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.74

Net Charge (pH 7.4) 5.24

Charge Density (pH 7.0) 0.1596

GRAVY Index-0.46

Hydrophobic Moment 0.58

Boman Index-0.11

Instability Index55.21

Aliphatic Index 43.33

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1681.93

LogP -19.41

H-bond Donors 66.0

H-bond Acceptors 61.0

Rotatable Bonds 133.0

Heavy Atoms 286.0

Ring Count 9.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207718 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)