Peptide Database

Peptide NameNeutrophil defensin 3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC162H266N58O42S6

DescriptionStandard

        VTCFCRRRGCASRERLIGYCRFGNTIYGLCCRR
    

Molecular Weight3890.60 Da

Isoelectric Point (pI)9.80

Net Charge (pH 7.0)6.68

Net Charge (pH 7.4) 6.37

Charge Density (pH 7.0) 0.2023

GRAVY Index-0.19

Hydrophobic Moment 0.49

Boman Index-0.27

Instability Index52.17

Aliphatic Index 59.09

Aromaticity 0.1212

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1671.26

LogP -19.14

H-bond Donors 71.0

H-bond Acceptors 55.0

Rotatable Bonds 128.0

Heavy Atoms 268.0

Ring Count 4.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408291 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

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