Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length257 amino acids

Chemical FormulaC1256H1974N338O366S7

DescriptionStandard

        TNPGFVVRITQAGLDYAQQQGIAILEKELAQLKLPNISGKSGELHYSLSRLHIPSFHLPHSRITPISNVGLQVSISNASVELDGDCWVKFLFIKGPGSFDLKVENISIKFILRLGSDTSGKPTISTSDCSARASKVGLHFSGKLAWVRGCDPAAPAQLCGLSVPQVCDNVAKSVHNELQTYIQTLPVTARIDDKIGINYTLVAPPRPTAQSLDADLKGEFCSLVHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNT
    

Molecular Weight27889.61 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)2.05

Net Charge (pH 7.4) 1.32

Charge Density (pH 7.0) 0.0080

GRAVY Index-0.01

Hydrophobic Moment 0.64

Boman Index0.11

Instability Index37.65

Aliphatic Index 94.09

Aromaticity 0.0817

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412867 VERIFIED: NO

Provenance & Taxonomy

OrganismMelospiza melodia (Song sparrow) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria