Peptide Database

Peptide Namenatriuretic peptide OmNP-e

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC172H280N54O56S2

DescriptionStandard

        SDSKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKQIPGGS
    

Molecular Weight4064.52 Da

Isoelectric Point (pI)7.81

Net Charge (pH 7.0)0.53

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0132

GRAVY Index-0.42

Hydrophobic Moment 0.55

Boman Index0.01

Instability Index50.96

Aliphatic Index 73.00

Aromaticity 0.0250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1752.99

LogP -24.51

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 132.0

Heavy Atoms 284.0

Ring Count 6.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077096 VERIFIED: YES

Provenance & Taxonomy

OrganismOxyuranus microlepidotus [Animal]

Familynatriuretic peptide OmNP-e

Tax ID111177

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0112896 VERIFIED: NO

Provenance & Taxonomy

OrganismOxyuranus microlepidotus [Animal]; Pseudechis australis [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0331422 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

Familynatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour