Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length481 amino acids

Chemical FormulaC2411H3789N637O666S13

DescriptionStandard

        MAARSLAAFGVVLAVCLALTAATNPGFVVRITQAGLDYAHQHGITVLQKELAKLKLPDISGDFPVRHLGKVRYEISSLNLRSFHLPYSRISLVPNVGLQVAISNAFAEVDGNWRVKFHFIRDHGSFNLEVKNVYIKIDLKLGSDASGKPTVSTSACSTRISSVDVHFSGKFGWLYNLFYGVVESRFKKILESKVCDSVVRSVSGDLQHYLQTLPVTAKIDAKAGIDYSLVAPPMATAQTLDVDLKGEFFSLAHRGAVPFPPPVLALPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSMIPKDVEFHLNTSTFAAFIPQLDKMYPNMLMKLRLSAPSAPFLSITPGGISLQPVVDIQAYAILPNTSLAHLFLLSLTGNVSATIDVKSGHIVGKLSVGRMKLSLKQSDVGTFQVRMLQSIMNIYASSILLPRVNERLAEGFPLPLPDRIQLSNILVQFHQNFLLLGADVHYTPRERR
    

Molecular Weight52771.59 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)9.89

Net Charge (pH 7.4) 8.73

Charge Density (pH 7.0) 0.0206

GRAVY Index0.20

Hydrophobic Moment 0.71

Boman Index0.15

Instability Index36.18

Aliphatic Index 103.58

Aromaticity 0.0956

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378954 VERIFIED: NO

Provenance & Taxonomy

OrganismChrysolophus pictus (Golden pheasant) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria