Peptide Database

Peptide NameMT-SC27EK

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC167H264N40O54S

DescriptionStandard

        MTWEEWDKKIEEYTKKIEELIKKSEEQQK
    

Molecular Weight3728.18 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-2.48

Net Charge (pH 7.4) -2.73

Charge Density (pH 7.0) -0.0857

GRAVY Index-1.79

Hydrophobic Moment 0.69

Boman Index-0.40

Instability Index78.85

Aliphatic Index 53.79

Aromaticity 0.1034

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1594.64

LogP -10.11

H-bond Donors 54.0

H-bond Acceptors 53.0

Rotatable Bonds 137.0

Heavy Atoms 262.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236904 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

PaperConserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors. Viruses. 2019 Jul 3;11(7):609. doi: 10.3390/v11070609. PMID: 31277353. PMID31277353 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31277353/

RECORD: Rec_0239423 VERIFIED: YES