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MYP_130256
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Basic Information
LAH4-L1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
26 amino acids
C132H228N38O27
Standard
Sequence
KKALLAHALHLLALLALHLAHALKKA
Physicochemical Analysis
2779.46 Da
10.48
4.10
3.69
0.1579
0.92
0.45
0.31
-0.18
180.77
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1009.62
-2.48
35.0
35.0
95.0
197.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010855 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
8.6±1.6 μM
MIC50
PMID34065185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34065185/
RECORD: Rec_0148304 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID22138072 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22138072/
RECORD: Rec_0148791 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus megaterium
5 μM
MIC50
PMID17005809;34065185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17005809/
RECORD: Rec_0169661 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
5 μM
MIC50
PMID17005809;34065185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17005809/
RECORD: Rec_0275368 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
LAH4-L1
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
PLDH assay
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
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