Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC941H1473N247O256S10

DescriptionStandard

        PMALAVAHEPMLLLAITDFVANSAAFTYFTAGALHRNISSDMLPQRFPLQLKTKSMGVFSPQLQKRYPDHPMELHLSARKQPLFSCRPDALHGTLFSSAEAFVVLPNATRVPVFLLNIDANVTGKPTISSNRLGGTLNPAYAMALSACPMVGSGSLSVPQVKKLENLLKFSLWLFGVPYANSEFCPHPVP
    

Molecular Weight20662.91 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.46

Net Charge (pH 7.4) 5.03

Charge Density (pH 7.0) 0.0287

GRAVY Index0.17

Hydrophobic Moment 0.54

Boman Index0.17

Instability Index47.21

Aliphatic Index 91.95

Aromaticity 0.0895

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7846.59

LogP -92.47

H-bond Donors 267.0

H-bond Acceptors 277.0

Rotatable Bonds 651.0

Heavy Atoms 1454.0

Ring Count 43.0

Amide Bonds 204.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349724 VERIFIED: NO

Provenance & Taxonomy

OrganismNycticryphes semicollaris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria