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MYP_130195
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Basic Information
Flt1-12
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
12 amino acids
C68H101N15O21S
Standard
Sequence
RPFVEMYSEIPE
Physicochemical Analysis
1496.68 Da
4.52
-2.23
-2.44
-0.1856
-0.57
0.58
-0.01
105.18
56.67
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
580.10
-2.76
19.0
20.0
45.0
105.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040957 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
VEGFR1 / Flt-1
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Flt-1-derived peptide
VEGF-induced angiogenesis / vascular permeability
Miles vascular permeability assay
PaperA small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0043939 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
RECORD: Rec_0051621 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
RECORD: Rec_0093246 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0151417 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID11311231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11311231/
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