Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC442H749N119O125S2

DescriptionStandard

        MKIKKVLAGTLGLGVVGSVLTLNQFSGSGLANLTLQYDISAVNAGRIVSALDWASDMGAVIGLAGAILGAGIGAAAISAAVAIAKRKLLKEGKKAAVLY
    

Molecular Weight9794.53 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.26

Charge Density (pH 7.0) 0.0555

GRAVY Index0.80

Hydrophobic Moment 0.77

Boman Index0.32

Instability Index5.01

Aliphatic Index 132.22

Aromaticity 0.0404

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3870.28

LogP -36.49

H-bond Donors 136.0

H-bond Acceptors 133.0

Rotatable Bonds 335.0

Heavy Atoms 688.0

Ring Count 5.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305407 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus VD184 [Bacterium]

FamilyBacteriocin

Tax ID1053242

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal