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MYP_130118
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Basic Information
BacR
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
14 amino acids
C75H144N32O15S2
Standard
Sequence
RRLCRIVVIRVCRR
Physicochemical Analysis
1798.28 Da
12.00
5.74
5.51
0.4100
0.24
0.50
-0.54
85.05
145.71
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
813.02
-6.75
35.0
23.0
62.0
124.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0374598 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
mitis
0.5 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0384518 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
64 μg/mL
MIC
PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0411983 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes ATCC 19615
8 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0426896 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-12
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis C621
8 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
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