Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC391H629N101O109S11

DescriptionStandard

        LAMRSLRLVFMVLFLLSYVPPGKNGSGMNPYIKEAFDKCWLMKDVCRKKCGKNEIDHIVCDNADVCCITEEEMPILVG
    

Molecular Weight8841.50 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.57

Charge Density (pH 7.0) -0.0026

GRAVY Index0.16

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index47.73

Aliphatic Index 94.87

Aromaticity 0.0769

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3347.91

LogP -23.93

H-bond Donors 119.0

H-bond Acceptors 121.0

Rotatable Bonds 296.0

Heavy Atoms 612.0

Ring Count 12.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318151 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence