Peptide Database

Peptide NamePMAP-23 [Q13W][K14W]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC151H229N43O27

DescriptionStandard

        RIIDLLWRVRRPWWPKFVTVWVR
    

Molecular Weight3078.71 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.56

Charge Density (pH 7.0) 0.2070

GRAVY Index-0.05

Hydrophobic Moment 0.76

Boman Index-0.05

Instability Index44.50

Aliphatic Index 118.26

Aromaticity 0.2174

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1142.15

LogP -0.68

H-bond Donors 44.0

H-bond Acceptors 32.0

Rotatable Bonds 92.0

Heavy Atoms 221.0

Ring Count 11.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034991 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetSNU-601

Activity37 μM

MethodIC50

RECORD: Rec_0072136 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

RECORD: Rec_0207071 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0271207 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetTumor cells: Jurkat

Activity23 μM

MethodIC50

RECORD: Rec_0310811 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic