Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length346 amino acids

Chemical FormulaC1681H2699N471O491S17

DescriptionStandard

        MSAYKAASYGVRRTVRDAKRRYRERLKSHFHQGDTRSMWQGLRTITDYKIKDTEMINADFTFANELNEFFAVSRTSRMQVVICFLMILTHTYADYPALKTVLSEKGLRDVSQMMAVWIQSKLKSTTIPEVHGGVDIGIGTVHYVISNHDGGSLDLAVYNIKIQTLLELGDDTGRVSITTVSCSDGIGGVNIQFHGGARSGTIDVHVLAAAKFSVVKPDGMLVPLFRLDVDGSFSGSALIDKKHLTGAFNMKKVLQSAALQLPYQTVMQLPEPPAKMAAKPEPPAKMAAKPEPPAKMAAKPEPPAKMAAKPEPPAKMAAAPELTDPPERPQATALRKHKENDTHTAR
    

Molecular Weight37908.38 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)10.47

Net Charge (pH 7.4) 9.57

Charge Density (pH 7.0) 0.0303

GRAVY Index-0.29

Hydrophobic Moment 0.96

Boman Index0.00

Instability Index46.49

Aliphatic Index 79.57

Aromaticity 0.0636

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333621 VERIFIED: NO

Provenance & Taxonomy

OrganismLabeo rohita [Bacterium]

FamilyBPI

Tax ID84645

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence