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MYP_130071
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Basic Information
Kunitzin-RE
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C87H144N24O19S2
Standard
Sequence
AAKIILNPKFRCKAAFC
Physicochemical Analysis
1894.35 Da
9.85
3.77
3.55
0.2219
0.55
0.32
0.09
14.05
92.35
0.1176
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
703.18
-4.25
26.0
25.0
62.0
132.0
3.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194638 VERIFIED: YES
Provenance & Taxonomy
Rana esculenta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
30 μM
MIC
PaperKunitzins: Prototypes of a new class of protease inhibitor from the skin secretions of European and Asian frogs
RECORD: Rec_0215267 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 25923
128 μM
MIC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0243944 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K88
64 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0257386 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 27853
128 μM
MIC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0259342 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. pullorum 7913
64 μM
MIC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
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