Peptide Database

Peptide NameDefensin heliomicin (Mutation: K23L, R24L)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC201H301N57O64S6

DescriptionStandard

        DKLIGSCVWGAVNYTSDCNGECLLRGYKGGHCGSFANVNCWCET
    

Molecular Weight4732.27 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-1.21

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0275

GRAVY Index-0.10

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index20.75

Aliphatic Index 59.77

Aromaticity 0.1136

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1951.99

LogP -23.57

H-bond Donors 74.0

H-bond Acceptors 70.0

Rotatable Bonds 151.0

Heavy Atoms 328.0

Ring Count 8.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0122044 VERIFIED: YES

Provenance & Taxonomy

OrganismHeliothis virescens [Animal]

FamilyDefensin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

RECORD: Rec_0239520 VERIFIED: YES