Peptide Database

Peptide NameLL-37 (17-29)[F11H]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC77H133N27O17

DescriptionStandard

        FKRIVQRIKDHLR
    

Molecular Weight1709.05 Da

Isoelectric Point (pI)11.72

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.2959

GRAVY Index-0.90

Hydrophobic Moment 0.91

Boman Index-0.51

Instability Index24.50

Aliphatic Index 112.31

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 759.33

LogP -4.99

H-bond Donors 28.0

H-bond Acceptors 22.0

Rotatable Bonds 61.0

Heavy Atoms 121.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397550 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetGram-negative bacteria: Escherichia coli (ATCC 25922)

Activity10 μM

MethodMIC

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