Peptide Database

Peptide NameBig gastrin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC177H256N40O55S

DescriptionStandard

        QLGPQDLPYLTADLSKKQGPWLEEEEAYGWMDF
    

Molecular Weight3856.23 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.23

Net Charge (pH 7.4) -5.45

Charge Density (pH 7.0) -0.1585

GRAVY Index-0.83

Hydrophobic Moment 0.36

Boman Index0.03

Instability Index70.36

Aliphatic Index 65.15

Aromaticity 0.1515

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1523.06

LogP -9.75

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 122.0

Heavy Atoms 273.0

Ring Count 10.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143619 VERIFIED: YES

Provenance & Taxonomy

OrganismDidelphis virginiana [Animal]

FamilyBig gastrin

Tax ID9267

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Other Mods18:Pyrrolidone carboxylic acid; 28:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour