Peptide Database

Peptide NameCystatin-11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC747H1145N195O210S9

DescriptionStandard

        MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVFAVPWFEQYKILNKSCSSD
    

Molecular Weight16505.85 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.66

Charge Density (pH 7.0) -0.0078

GRAVY Index-0.38

Hydrophobic Moment 0.70

Boman Index-0.02

Instability Index38.94

Aliphatic Index 82.61

Aromaticity 0.1232

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6579.58

LogP -51.27

H-bond Donors 227.0

H-bond Acceptors 223.0

Rotatable Bonds 547.0

Heavy Atoms 1161.0

Ring Count 31.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067287 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCystatin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Protease inhibitor Thiol protease inhibitor Enzyme Inhibitor Non-hemolytic

TargetGram Negative Bacteria