Peptide Database

Peptide NamePtALF7 (Portunus trituberculatus anti-lipopolysaccharide factor isoform 7; crabs, Arthropods, ani

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC426H655N109O103S7

DescriptionStandard

        MRKGVVTGLFVALVVMCLYLPQPCEAQYEALTAAILTKLSKMWHSDTLNFLGHTCHVSRTPTVKRFKLYWKGKFWCPGWA
    

Molecular Weight9175.88 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.27

Charge Density (pH 7.0) 0.0840

GRAVY Index0.19

Hydrophobic Moment 0.54

Boman Index0.16

Instability Index22.14

Aliphatic Index 86.50

Aromaticity 0.1375

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3348.26

LogP -20.37

H-bond Donors 123.0

H-bond Acceptors 120.0

Rotatable Bonds 291.0

Heavy Atoms 645.0

Ring Count 22.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0391269 VERIFIED: YES

Provenance & Taxonomy

OrganismPortunus trituberculatus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitystereochemistry not specified [Other]

DisulfideDisulfide bond(s) reported

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetVibrio alginolyticus

Activity0.51-1.02 μM

MethodMIC

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