Peptide Database

Peptide NameHaNP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC166H271N63O42S6

DescriptionStandard

        VTCFCRRRGCASRERHIGYCRFGNTIYRLCCRR
    

Molecular Weight4013.71 Da

Isoelectric Point (pI)10.20

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.41

Charge Density (pH 7.0) 0.2352

GRAVY Index-0.52

Hydrophobic Moment 0.76

Boman Index-0.41

Instability Index68.77

Aliphatic Index 47.27

Aromaticity 0.1212

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1761.84

LogP -20.59

H-bond Donors 75.0

H-bond Acceptors 57.0

Rotatable Bonds 132.0

Heavy Atoms 277.0

Ring Count 5.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057497 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide3-31; 5-20; 10-30

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetPseudomonas aeruginosa

RECORD: Rec_0060464 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide3-31; 5-20; 10-30

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCryptococcus neoformans

RECORD: Rec_0081307 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0110502 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCryptococcus neoformans

RECORD: Rec_0112835 VERIFIED: YES

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide3-31; 5-20; 10-30

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetSalmonella serotype krefeld

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