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MYP_129896
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Basic Information
Brevinin CTcu5 [L1H]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C103H174N30O24S2
Standard
Sequence
HIAGLAANFLPQILCKIARKC
Physicochemical Analysis
2280.80 Da
9.50
2.83
2.54
0.1345
0.73
0.74
0.22
46.76
130.48
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
865.33
-5.68
31.0
30.0
75.0
159.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081617 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: 30
PaperPubMed PMID: 25997127 PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0124295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus MTCC 9542
100 μg/mL
MIC
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0160945 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio cholerae
25 μg/mL
MIC
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0226271 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human epidermoid carcinoma A431[50-60% Cytotoxicity >100 microg/ml]
PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
RECORD: Rec_0281544 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25997127 PMID25997127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25997127/
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