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MYP_129866
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Basic Information
Angiotensin I converting enzyme inhibitior 1
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
9 amino acids
C41H72N12O14
Standard
Sequence
RASDPLLSV
Physicochemical Analysis
957.08 Da
5.84
-0.24
-0.44
-0.0265
0.27
0.53
0.02
8.89
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
426.99
-4.73
15.0
14.0
29.0
67.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098974 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Angiotensin
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
4.70 μM
IC50
RECORD: Rec_0311715 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
426.25
PaperZambrowicz A., Eckert E., Pokora M., Bobak ?., D?browska A., Szo?tysik M., Trziszka T., Chrzanowska J.. Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467.
RECORD: Rec_0370645 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperZambrowicz A., Eckert E., Pokora M., Bobak ?., D?browska A., Szo?tysik M., Trziszka T., Chrzanowska J.. Antioxidant and antidiabetic activities of peptides isolated from a hydrolysate of an egg-yolk protein by-product prepared with a proteinase from Asian pumpkin (Cucurbita ficifolia). RSC Adv. 5, 10460-10467.
RECORD: Rec_0399103 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
9031.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
4.7
PaperEckert E., Zambrowicz A., Pokora M., Setner B., D?browska A., Szo?tysik M., Szewczuk Z., Polanowski A., Trziszka T., Chrzanowska J.. Egg-yolk protein by-product as a source of ACE-inhibitory peptides obtained with using unconventional proteinase from Asian pumpkin (Cucurbita ficifolia). Journal of Proteomics 110, 107-116.