Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC46H67N15O13

DescriptionStandard

        EHWSGLRPG
    

Molecular Weight1038.12 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.30

Charge Density (pH 7.0) -0.0084

GRAVY Index-1.28

Hydrophobic Moment 0.35

Boman Index-0.10

Instability Index40.11

Aliphatic Index 43.33

Aromaticity 0.1111

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 451.23

LogP -4.10

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 30.0

Heavy Atoms 74.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029735 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0149710 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGnRH

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0154247 VERIFIED: YES

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyGnRH

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour