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MYP_129755
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
13 amino acids
C80H135N25O17
Standard
Sequence
RLFDKIRQVIRKF
Physicochemical Analysis
1719.09 Da
11.72
3.76
3.55
0.2892
-0.44
0.97
-0.39
14.68
112.31
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
730.65
-3.72
27.0
21.0
61.0
122.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0048591 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0147494 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Bos taurus [Animal]
Cathelicidin
9606,9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antiviral Multifunction
CEM-SS
>58.1 μM
IC50
PaperAnti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins. PMID18591279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18591279/
RECORD: Rec_0157492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20080125359A1/en PatentUS 2008/0125359 A1
RECORD: Rec_0186892 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Entry inhibition
HIV-1IIIB | CEM-SS cells
58.1 μM
EC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperAnti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins. | Wang G, Watson KM, Buckheit RW Jr. | Antimicrob Agents Chemother. 2008 Sep;52(9):3438-40. | DOI:10.1128/AAC.00452-08 | PMID:18591279 PMID18591279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18591279/
RECORD: Rec_0276413 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antiviral
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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