Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H881N149O167S4

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDTGRSTVSISKVSVTAIFSTPLDNTGHTSMSLTSCRTTPGDIDIKLNGKR
    

Molecular Weight12332.99 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index-0.04

Hydrophobic Moment 0.53

Boman Index0.09

Instability Index19.03

Aliphatic Index 89.74

Aromaticity 0.0702

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5069.75

LogP -58.26

H-bond Donors 182.0

H-bond Acceptors 177.0

Rotatable Bonds 407.0

Heavy Atoms 866.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169649 VERIFIED: NO

Provenance & Taxonomy

OrganismCrotophaga sulcirostris [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria