MYP_129736
Basic Information
Cyclotide vibi-D (Plant defensin)
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Standard
29 amino acids
C122H193N37O40S6
Standard
Sequence
GLPVCGETCFGGRCNTPGCTCSYPICTRN
Physicochemical Analysis
3010.45 Da
7.78
0.70
0.41
0.0242
-0.03
0.27
0.06
52.66
36.90
0.0690
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1220.41
-18.18
48.0
47.0
89.0
205.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017807 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Defensin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21; 9-23; 14-28
Bio-Activity Profile
Cytotoxic
RECORD: Rec_0086157 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0135053 VERIFIED: NO
Provenance & Taxonomy
Viola biflora [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0150651 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Defensin
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-21; 9-23; 14-28
Bio-Activity Profile
Cytotoxic
Human lymphoma cell line U-937 GTB
30 μM
IC50
RECORD: Rec_0219699 VERIFIED: YES
Provenance & Taxonomy
Viola biflora [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
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