Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length560 amino acids

Chemical FormulaC2640H4176N758O825S20

DescriptionStandard

        MNRMSVHGKGQGLHGDRTTTGAMCITSLPNASENNRGVLRIDDVTTACPKCGKVGRIISGDARATYNGRATAVDGALVLCGCPSGSNRLIAPLGRLASERSSSAEQPPTSMAQHSAQVAKKPEAETMTAGQDKCSTPVFAKSRERGDGNTEAGTEPETHENFALMGYFRSVPLSEPEQHAQSAKRPASPPPEPEKPWYKKLFGGATAAAPAVAAPVAASTVFPSGSAALEWVGGRFITAGSWAVRAVVPFGEIAAAGAGAPIAVALIGMMPRTLNSGEQDFINQMRLAQLAESGGKAPTRVRFRWEDDGHGRLSPKGYHTPTESGLSEVPVREMKLNTKTGLYEFTTEGVKPVTIYWNPDKLELDIPSNTGHQDSPSLPSSITVLPIPEKVGSDIESYPAPTEGDFEDYILVFLGTDMPPIYIYLSKPPVEFLDVELYSDFKRRSRQGKYEADHMPSAAAVRAHFKRLYPDADSEDLDAYAQDVASIVVPKEVHRKLSETYGGRNTDAQIEVDSRDLRAAVDRNLEAIRSALKEHGATDAKIEAARTKMHKLNDRMGLYK
    

Molecular Weight60375.28 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-4.33

Net Charge (pH 7.4) -5.44

Charge Density (pH 7.0) -0.0077

GRAVY Index-0.46

Hydrophobic Moment 0.72

Boman Index-0.03

Instability Index46.11

Aliphatic Index 70.30

Aromaticity 0.0643

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51715.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367279 VERIFIED: YES

Provenance & Taxonomy

OrganismHafnia alvei [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)