Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length164 amino acids

Chemical FormulaC823H1328N238O239S7

DescriptionStandard

        MNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLSVAKSELDKAIGRNCNGVITKNEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRCALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVIATFRTGTWDAYKNL
    

Molecular Weight18605.25 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)8.58

Net Charge (pH 7.4) 8.24

Charge Density (pH 7.0) 0.0523

GRAVY Index-0.37

Hydrophobic Moment 0.71

Boman Index-0.07

Instability Index37.16

Aliphatic Index 88.66

Aromaticity 0.0854

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 25565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7831.18

LogP -77.38

H-bond Donors 277.0

H-bond Acceptors 256.0

Rotatable Bonds 635.0

Heavy Atoms 1307.0

Ring Count 21.0

Amide Bonds 180.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262725 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella phage SHBML-50-1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic