Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC469H736N122O135S9

DescriptionStandard

        MAIVEVWENVLNSLMKSFETGDKKLVFRPWKISNVGYSSFTIATCTLVDPDRCTKSFGYCRRRCFKYEKQIDICLSPSKICCIERLFEED
    

Molecular Weight10532.18 Da

Isoelectric Point (pI)8.17

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.10

Charge Density (pH 7.0) 0.0161

GRAVY Index-0.16

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index43.28

Aliphatic Index 77.89

Aromaticity 0.1222

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4181.63

LogP -35.93

H-bond Donors 155.0

H-bond Acceptors 146.0

Rotatable Bonds 352.0

Heavy Atoms 735.0

Ring Count 16.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257135 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence