Peptide Database

Peptide NameIntestinal peptide PHI-27

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC136H215N35O42

DescriptionStandard

        HADGVFTSDYSRLLGQLSAKKYLESLI
    

Molecular Weight3012.37 Da

Isoelectric Point (pI)6.75

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0056

GRAVY Index-0.10

Hydrophobic Moment 0.52

Boman Index0.06

Instability Index20.75

Aliphatic Index 104.81

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1259.14

LogP -11.71

H-bond Donors 45.0

H-bond Acceptors 43.0

Rotatable Bonds 101.0

Heavy Atoms 213.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061627 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyGlucagon

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0206197 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 14.8%, E 14.8%, T 59.3%, C 11.1% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0220657 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0404698 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyIntestinal peptide PHI

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour