Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC254H419N75O84S8

DescriptionStandard

        VATCTLVDADRCTKRYGRCKRDCLEIEKQIDICSSPRKICCTERLYEEDDMF
    

Molecular Weight6124.02 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-1.32

Net Charge (pH 7.4) -1.66

Charge Density (pH 7.0) -0.0254

GRAVY Index-0.58

Hydrophobic Moment 0.81

Boman Index-0.28

Instability Index73.80

Aliphatic Index 67.50

Aromaticity 0.0577

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2629.34

LogP -27.62

H-bond Donors 101.0

H-bond Acceptors 91.0

Rotatable Bonds 210.0

Heavy Atoms 421.0

Ring Count 4.0

Amide Bonds 52.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0079731 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes troglodytes [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KL3/entry; https://bblserver.org.in/ampdb/

RECORD: Rec_0179439 VERIFIED: NO