Peptide Database

Peptide NameBovine Beta-defensin 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H291N55O44S8

DescriptionStandard

        PLSCCRNIGICVPIKCSGNMRQIGTCLGALVKCCRRW
    

Molecular Weight4053.98 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.89

Net Charge (pH 7.4) 5.72

Charge Density (pH 7.0) 0.1591

GRAVY Index0.40

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index64.00

Aliphatic Index 92.16

Aromaticity 0.0270

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1593.53

LogP -17.36

H-bond Donors 65.0

H-bond Acceptors 58.0

Rotatable Bonds 134.0

Heavy Atoms 276.0

Ring Count 4.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250195 VERIFIED: YES

Provenance & Taxonomy

OrganismBison bison [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)