Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC406H650N114O109S10

DescriptionStandard

        MPGSFGGLPRSPVAMTQLLLLIVALLVLGHVPPGRSEFKRCWKGQGACRTYCTRHETYMHMCPDASLCCVAYGIRPLPSKTESV
    

Molecular Weight9192.85 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0560

GRAVY Index0.13

Hydrophobic Moment 0.55

Boman Index0.11

Instability Index76.87

Aliphatic Index 82.38

Aromaticity 0.0714

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3478.19

LogP -31.71

H-bond Donors 128.0

H-bond Acceptors 127.0

Rotatable Bonds 289.0

Heavy Atoms 639.0

Ring Count 18.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187115 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx canadensis [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0297732 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx pardinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence