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MYP_129521
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Basic Information
Amythiamicin A B [Cleaved into: Amythiamicin C D]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antibiotic activity
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
14 amino acids
C48H81N15O19S6
Standard
Sequence
SCNCVCGVCCSCSP
Physicochemical Analysis
1364.64 Da
5.23
-0.60
-0.89
-0.0428
1.11
0.22
0.23
79.80
41.43
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
536.61
-10.42
24.0
25.0
39.0
88.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0152723 VERIFIED: YES
Provenance & Taxonomy
Amycolatopsis sp. [other]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans 3147
50 μg/mL
MIC
PMID8040071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8040071/
RECORD: Rec_0156647 VERIFIED: YES
Provenance & Taxonomy
Amycolatopsis sp. [Animal]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis NRRL B-558
0.2 μg/mL
MIC
PMID8040071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8040071/
RECORD: Rec_0176349 VERIFIED: YES
Provenance & Taxonomy
Amycolatopsis sp. [other]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Providencia rettgeri GN311
100 μg/mL
MIC
PMID8040071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8040071/
RECORD: Rec_0201286 VERIFIED: YES
Provenance & Taxonomy
Amycolatopsis sp. [other]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus vulgaris OX19
100 μg/mL
MIC
PMID8040071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8040071/
RECORD: Rec_0212690 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 50.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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