Peptide Database

Peptide NameDUP-1

Function Ontology

Anticancer

Anticancer ▸ Tumor Homing Peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC63H94N22O21

DescriptionStandard

        FRPNRAQDYNTN
    

Molecular Weight1495.56 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0634

GRAVY Index-2.12

Hydrophobic Moment 0.31

Boman Index-0.58

Instability Index21.67

Aliphatic Index 8.33

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 748.55

LogP -10.28

H-bond Donors 25.0

H-bond Acceptors 22.0

Rotatable Bonds 46.0

Heavy Atoms 106.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375387 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Tumor Homing Peptide Cell-penetrating Drug Delivery Vehicle Anticancer

TargetDU-145 and PC-3 prostate carcinoma cells

MethodPhage-display selection; cell-binding/internalization assay

RECORD: Rec_0420853 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 33.3%, C 66.7% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Drug Delivery Vehicle Tumor Homing Peptide