Peptide Database

Peptide NameToxin LyeTx 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC135H226N36O30

DescriptionStandard

        IWLTALKFLGKNLGKHLAKQQLAKL
    

Molecular Weight2833.46 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1937

GRAVY Index0.15

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index18.11

Aliphatic Index 136.80

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1085.79

LogP -4.91

H-bond Donors 37.0

H-bond Acceptors 36.0

Rotatable Bonds 100.0

Heavy Atoms 201.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395080 VERIFIED: YES

Provenance & Taxonomy

OrganismLycosa erythrognatha [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetEscherichia coli

Activity7.8 μM

MethodMIC

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