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MYP_129425
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Basic Information
Toxin LyeTx 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
25 amino acids
C135H226N36O30
Standard
Sequence
IWLTALKFLGKNLGKHLAKQQLAKL
Physicochemical Analysis
2833.46 Da
10.60
4.84
4.58
0.1937
0.15
0.63
0.13
18.11
136.80
0.0800
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1085.79
-4.91
37.0
36.0
100.0
201.0
4.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010289 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
3.79 μM
MIC
PMID19946788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19946788/
RECORD: Rec_0052519 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans
13.2 μM
MIC
PMID19946788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19946788/
RECORD: Rec_0059455 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
LyeTx
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperAmino Acids. 2010 Jun;39(1):135-44 | http://www.ncbi.nlm.nih.gov/pubmed/19946788 PMID19946788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19946788/
RECORD: Rec_0101862 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Rabbit RBCs
1.3
ED50
PMID19946788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19946788/
RECORD: Rec_0114600 VERIFIED: NO
Provenance & Taxonomy
Lycosa erythrognatha [Animal]; Scaptocosa raptoria [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Toxin Antimicrobial
Escherichia coli, Staphylococcus aureus and fungi, Candida krusei and
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