Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC388H612N110O104S11

DescriptionStandard

        MALIRKTFCFVFAVFFILVQQPSGCQAGLEFSEPFPSGGFAVCESCKLGRGRCRKECLENEKPDGRCRLNFLCCRQKM
    

Molecular Weight8834.40 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)4.42

Net Charge (pH 7.4) 4.06

Charge Density (pH 7.0) 0.0567

GRAVY Index0.02

Hydrophobic Moment 0.43

Boman Index-0.01

Instability Index51.24

Aliphatic Index 65.00

Aromaticity 0.1154

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3453.05

LogP -32.34

H-bond Donors 128.0

H-bond Acceptors 120.0

Rotatable Bonds 295.0

Heavy Atoms 613.0

Ring Count 13.0

Amide Bonds 83.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0348149 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic