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MYP_129419
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Basic Information
Temporin-LK1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C97H144N18O20S2
Standard
Sequence
FFPLLFGALSSMMPKLF
Physicochemical Analysis
1946.42 Da
8.75
0.76
0.55
0.0447
1.35
0.36
0.57
46.24
97.65
0.2353
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
577.82
0.59
19.0
23.0
59.0
137.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0229584 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0231515 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ML-35P
30 μg/mL
MIC
PaperFive novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii.
RECORD: Rec_0236699 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2002
5 μg/mL
MIC
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0292781 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit RBC
100 μg/mL
Hemolysis
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0326348 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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