Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC311H494N78O81S8

DescriptionStandard

        MKPFLVTLAVLLLFFQVTAGSIEKCWNFRGSCRDECLKNEKVYVFCMSGKLCCLKPKDQP
    

Molecular Weight6878.24 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.12

Charge Density (pH 7.0) 0.0574

GRAVY Index0.21

Hydrophobic Moment 0.36

Boman Index0.08

Instability Index42.66

Aliphatic Index 86.00

Aromaticity 0.1167

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2555.82

LogP -17.89

H-bond Donors 93.0

H-bond Acceptors 93.0

Rotatable Bonds 229.0

Heavy Atoms 478.0

Ring Count 11.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110551 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyBeta-defensin; Defensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic