Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC774H1209N225O219S6

DescriptionStandard

        MSKVQFKPRKETKYIFVHCSATRPSQDVGVREIRQWHKERGWLDVGYHYVIKRDGTIETGRSLEAVGSHVKGYNEVSVGICLVGGIDDQGKPNANFTVAQMESLKHLLARTGETYPQAQIMAHHDVAPKACPSFHVRRWLKGDGLITWYSKEI
    

Molecular Weight17362.65 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)6.18

Net Charge (pH 7.4) 5.47

Charge Density (pH 7.0) 0.0404

GRAVY Index-0.51

Hydrophobic Moment 0.75

Boman Index-0.05

Instability Index41.77

Aliphatic Index 75.75

Aromaticity 0.0915

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7150.61

LogP -67.81

H-bond Donors 254.0

H-bond Acceptors 239.0

Rotatable Bonds 576.0

Heavy Atoms 1224.0

Ring Count 32.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328756 VERIFIED: NO

Provenance & Taxonomy

OrganismMorganella phage vB_MmoP_MP2 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic