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MYP_129389
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Basic Information
Oxyopinin 2a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
37 amino acids
C189H314N54O49
Standard
Sequence
GKFSVFGKILRSIAKVFKGVGKVRKQFKTASDLDKNQ
Physicochemical Analysis
4126.85 Da
10.79
7.75
7.54
0.2096
-0.38
0.95
-0.13
5.55
78.92
0.1081
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1727.67
-16.53
61.0
57.0
149.0
292.0
4.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176992 VERIFIED: YES
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
Escherichia coli
12.5 μM
MIC
PaperOxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
RECORD: Rec_0237156 VERIFIED: YES
Provenance & Taxonomy
Oxyopes kitabensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
Staphylococcus aureus
6.2 μM
MIC
PaperOxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins
RECORD: Rec_0238008 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Insecticidal Hemolytic
PaperPubMed PMID: 11976325 PMID11976325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
RECORD: Rec_0238948 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Insecticidal
Sheep erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11976325/ PMID11976325 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11976325/
RECORD: Rec_0241470 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Oxyopinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
Paper蜘蛛抗菌肽研究进展; Advances in spider antimicrobial peptides. [J].生命科学,2014,26(10):1090-1095. DOI:10.13376/j.cbls/2014156. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37242
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