Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC327H514N80O87S9

DescriptionStandard

        MELRCVLLLVLMVILALHTKGSEAVSFPWSCAALNGVCRQGACLPSELYFGPLGCGKESLCCVSYFF
    

Molecular Weight7246.65 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-0.47

Net Charge (pH 7.4) -0.86

Charge Density (pH 7.0) -0.0071

GRAVY Index0.89

Hydrophobic Moment 0.49

Boman Index0.33

Instability Index40.17

Aliphatic Index 109.10

Aromaticity 0.1045

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2595.31

LogP -18.37

H-bond Donors 97.0

H-bond Acceptors 97.0

Rotatable Bonds 231.0

Heavy Atoms 503.0

Ring Count 12.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224845 VERIFIED: NO

Provenance & Taxonomy

OrganismSilurus meridionalis [Animal]

FamilyDefensin

Tax ID175797

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal