Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC588H956N168O185S9

DescriptionStandard

        MKLLLLALPVLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCVPSNEDHRRVPMTSPTPLSDSTPGIIDDILTVRFTTDYFEVSSKKDMVEESEAGRGTETSLPNVHHSS
    

Molecular Weight13627.48 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0015

GRAVY Index-0.42

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index52.62

Aliphatic Index 78.37

Aromaticity 0.0407

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5653.03

LogP -62.82

H-bond Donors 201.0

H-bond Acceptors 198.0

Rotatable Bonds 450.0

Heavy Atoms 950.0

Ring Count 19.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264593 VERIFIED: YES

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9597

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

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